@tm_hrvh asks: Why don’t edibles work on me? 🤔
Great question!! This is something that affects many people, and is something that I get frequently asked at the shop!
Why don’t edibles work on me?
According to Dr.Russo, a researcher of pharmacokinetics, there may be 2 explanations for this!
1. You may have an Endocannabinoid deficiency. Remember how each human has an Endocannabinoid system? Well, that system is responsible for producing the cannabinoid receptors that interact with THC. If your body isn’t producing enough of them, it may have a hard time binding to 11-Hydroxy THC molecules (that’s THC after it’s been converted in the liver) and therefore, edibles could have little, to no effect. This is common in people who suffer from migraines, IBS, and fibromyalgia.
2.You could have too much Pregnenolone in your body. Pregnenolone is a hormone that protects the brain from CB1 receptor overactivation. Our CB1 receptors are found in large quantities in our brains, meaning that the Preg hormone could potentially block or lessen the effects of certain types of THC!
One tip I tell my customers to aid with edible activation, is to take them on a full stomach! THC binds easiest to fat, so fatty foods like nuts, beans, burgers, etc, might just help!
What do you think? Have you ever had a problem with edibles? Let me know your questions in the comments! 😁🌿💨
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Alejandro Perez is the owner of CannaQuestions, an educational community for cannabis consumers. Find his page on Instagram @cannaquestions, or visit the official website cannaquestionsofficial.com!